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How to Take Dapoxetine - Dosage, Interactions and Precautions

 Dapoxetine is a selective serotonin reuptake inhibitor drug developed specifically for the treatment of premature ejaculation. It increases ejaculation time and may improve ejaculation control. It starts working very quickly, so it's done when you're going to have sex, rather than every day. Depoxetine pills should be taken 1-3 hours before sexual intercourse. Premature ejaculation is the term used when a man orgasms (ejaculates) faster than he or his partner would like. For some men, this may be temporary and may go away on its own. For others, prescribed treatments such as dapoxetine tablets may be helpful. Do not take more than one tablet in 2 hours. Dapoxetine is not for regular daily use - you should only take it before you plan to have sex. The tablet has a bitter taste, so swallow it whole without chewing. You can take it with or without food. 



HOW TO USE:


Take dapoxetine as it is directly administered by your doctor. The recommended dose is one tablet (30mg), to be taken as needed, about 1-3 hours before sexual activity.

Do not take more than one tablet in 2 hours. DAPOXETINE belongs to a class of drugs known as selective serotonin reuptake inhibitors that are mainly used to treat premature ejaculation in adult males between the ages of 18 and 6. Premature ejaculation occurs when a man ejaculate (orgasm) faster with less sexual stimulation than before the man or his partner wanted. This can lead to problems in the sexual relationship. 





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DAPOXETINE contains "Dapoxetine", which increases the level of serotonin in the nervous system; this increases ejaculation time and improves ejaculation control. Drug interactions There may be significant increases in serum dapoxetine concentrations and exposure to strong CYP2D6 (Cytochrome P 50 2D6) inhibitors (eg fluoxetine) and moderate CYP3A (Cytochrome P 50 3A ) inhibitors (eg fluconazole, verapamil, amprenavir, aprepitant, clarithromycin). 

There may be an increased risk of abnormal bleeding with agents known to affect platelet function (eg, warfarin, aspirin, NSAIDs, antiplatelet agents, atypical antipsychotics). 

Orthostatic tolerance may be impaired with α-adrenergic receptor antagonists, nitrates or PDE5 inhibitors.


 

Potentially fatal: increased serum concentrations and exposure to strong CYP3A inhibitors (eg, ketoconazole, ritonavir, nefazodone, telithromycin). May increase risk of serotonin syndrome with MAOIs, other SSRIs, SNRIs, TCAs, and other agents with serotonergic effects (eg, tryptophan, triptans, tramadol, lithium). 



It is possible that inhibition of thioridazine metabolism leads to increased thioridazine levels which may lead to prolongation of the QTc interval. Food interactions Concomitant use of alcohol may increase the incidence or severity of alcohol-related effects (eg, dizziness, somnolence) and may also increase neurocardiogenic side effects (eg, fainting); Avoid combining. 






Avoid drinking grapefruit juice within 2 hours of administration as it may increase serum dapoxetine concentrations. The plasma concentrations and exposures of the active radical of dapoxetine can be increased by approximately 6% and 90%, respectively, which may lead to the incidence and severity of adverse reactions related to dapoxetine. associated with a higher dose. Therefore, caution should be exercised when increasing the dose of dapoxetine to 60mg.



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